Neuroprotective Capability of Narcissoside in 6-OHDA-Exposed Parkinson's Disease Models through Enhancing the MiR200a/Nrf-2/GSH Axis and Mediating MAPK/Akt Associated Signaling Pathway

• Hoofdauteurs: Ru-Huei Fu (Auteur), Chia-Wen Tsai (Auteur), Shih-Ping Liu (Auteur), Shao-Chih Chiu (Auteur), Yen-Chuan Chen (Auteur), Yu-Ting Chiang (Auteur), Yun-Hua Kuo (Auteur), Woei-Cherng Shyu (Auteur), Shinn-Zong Lin (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

We assessed the antioxidant potential of narcissoside from <i>Sambucus nigra</i> flowers (elderflowers) in Parkinson's disease models in vitro and in vivo. The results showed that narcissoside lessened the 6-hydroxydopamine (6-OHDA)-induced increase in reactive oxygen species (ROS)...