Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-Whitney Equation with Cellular Automata on Microtomographic and Algorithmically Generated Surfaces

• Main Authors: Reiji Yokoyama (Author), Go Kimura (Author), Christian M. Schlepütz (Author), Jörg Huwyler (Author), Maxim Puchkov (Author)
• Formato: Libro
• Publicado: MDPI AG, 2018-12-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Manufacturing parameters may have a strong impact on the dissolution and disintegration of solid dosage forms. In line with process analytical technology (PAT) and quality by design approaches, computer-based technologies can be used to design, control, and improve the quality of pharmaceutical comp...