Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-Whitney Equation with Cellular Automata on Microtomographic and Algorithmically Generated Surfaces

• Egile Nagusiak: Reiji Yokoyama (Egilea), Go Kimura (Egilea), Christian M. Schlepütz (Egilea), Jörg Huwyler (Egilea), Maxim Puchkov (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2018-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Manufacturing parameters may have a strong impact on the dissolution and disintegration of solid dosage forms. In line with process analytical technology (PAT) and quality by design approaches, computer-based technologies can be used to design, control, and improve the quality of pharmaceutical comp...