Population Pharmacokinetics of Magnesium Sulfate in Preeclampsia and Associated Factors

• Main Authors: Tatiana Xavier da Costa (Author), Francine Johansson Azeredo (Author), Marcela Abbott Galvão Ururahy (Author), Miguel Adelino da Silva Filho (Author), Rand Randall Martins (Author), Antonio Gouveia Oliveira (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background and Objective The pharmacokinetic basis of magnesium sulphate (MgSO4) dosing regimens for preeclampsia (PE) prophylaxis and treatment is not clearly established. The aim of study is to develop a population pharmacokinetic (PK) model of MgSO4 in PE, and to determine key covariates...