San-Huang-Yi-Shen Capsule Ameliorates Diabetic Nephropathy in Rats Through Modulating the Gut Microbiota and Overall Metabolism

• Main Authors: Xiuhai Su (Author), Wenxia Yu (Author), Airu Liu (Author), Congxiang Wang (Author), Xiuzhen Li (Author), Juanjuan Gao (Author), Xiaofei Liu (Author), Wenhui Jiang (Author), Yue Yang (Author), Shuquan Lv (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

San-Huang-Yi-Shen capsule (SHYS) has been used in the treatment of diabetic nephropathy (DN) in clinic. However, the mechanisms of SHYS on DN remain unknown. In this study, we used a high-fat diet (HFD) combined with streptozotocin (STZ) injection to establish a DN rat model. Next, we used 16S rRNA...