Intranasal Administration of Nanovectorized Docosahexaenoic Acid (DHA) Improves Cognitive Function in Two Complementary Mouse Models of Alzheimer's Disease

• Main Authors: Charleine Zussy (Author), Rijo John (Author), Théo Urgin (Author), Léa Otaegui (Author), Claire Vigor (Author), Niyazi Acar (Author), Geoffrey Canet (Author), Mathieu Vitalis (Author), Françoise Morin (Author), Emmanuel Planel (Author), Camille Oger (Author), Thierry Durand (Author), Shinde L. Rajshree (Author), Laurent Givalois (Author), Padma V. Devarajan (Author), Catherine Desrumaux (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Polyunsaturated fatty acids (PUFAs) are a class of fatty acids that are closely associated with the development and function of the brain. The most abundant PUFA is docosahexaenoic acid (DHA, 22:6 <i>n</i>-3). In humans, low plasmatic concentrations of DHA have been associated with impai...