Diterpenoids inhibit ox-LDL-induced foam cell formation in RAW264.7 cells by promoting ABCA1 mediated cholesterol efflux

• Main Authors: Cheng Zhang (Author), Xuewen Wu (Author), Pengmin Shi (Author), Hongyu Ma (Author), Fei Fang (Author), Qianlang Feng (Author), Shuang Zhao (Author), Ruipu Zhang (Author), Jinyuan Huang (Author), Xinting Xu (Author), Weilie Xiao (Author), Guang Cao (Author), Xu Ji (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Atherosclerosis is the main cause of many cardiovascular diseases and contributes to morbidity and mortality worldwide. The formation of macrophage-derived foam cells plays a critical role in the early stage of atherosclerosis pathogenesis. Diterpenoids found in the flowers of Callicar...