Anti-Niemann Pick C1 Single-Stranded Oligonucleotides with Locked Nucleic Acids Potently Reduce Ebola Virus Infection In Vitro

Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus. Here, we selected the host factor Niemann-Pick C1 (NPC1), which has been shown to be esse...

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Main Authors: Anne Sadewasser (Author), Erik Dietzel (Author), Sven Michel (Author), Michael Klüver (Author), Markus Helfer (Author), Tamara Thelemann (Author), Richard Klar (Author), Markus Eickmann (Author), Stephan Becker (Author), Frank Jaschinski (Author)
Format: Book
Published: Elsevier, 2019-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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