Anti-Niemann Pick C1 Single-Stranded Oligonucleotides with Locked Nucleic Acids Potently Reduce Ebola Virus Infection In Vitro
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus. Here, we selected the host factor Niemann-Pick C1 (NPC1), which has been shown to be esse...
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Main Authors: | Anne Sadewasser (Author), Erik Dietzel (Author), Sven Michel (Author), Michael Klüver (Author), Markus Helfer (Author), Tamara Thelemann (Author), Richard Klar (Author), Markus Eickmann (Author), Stephan Becker (Author), Frank Jaschinski (Author) |
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Format: | Book |
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Elsevier,
2019-06-01T00:00:00Z.
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