Muscarinic receptor M3 activation promotes fibrocytes contraction

• Main Authors: Pauline Henrot (Author), Edmée Eyraud (Author), Elise Maurat (Author), Sophie Point (Author), Guillaume Cardouat (Author), Jean-François Quignard (Author), Pauline Esteves (Author), Thomas Trian (Author), Pierre-Olivier Girodet (Author), Roger Marthan (Author), Maéva Zysman (Author), Patrick Berger (Author), Isabelle Dupin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fibrocytes are monocyte-derived cells able to differentiate into myofibroblasts-like cells. We have previously shown that they are increased in the bronchi of Chronic Obstructive Pulmonary Disease (COPD) patients and associated to worse lung function. COPD is characterized by irreversible airflow ob...