Study of the antiarrhythmic activity of linear alkoxyphenylazalkanes in the model of reperfusion arrythmias in rats

• Main Authors: V. V. Barchukov (Author), V. N. Stolyaruk (Author), I. B. Tsorin (Author), M. B. Vititnova (Author), S. А. Kryzhanovskii (Author), T. Yu. Vorobieva (Author), V. E. Biryukova (Author), G. V. Mokrov (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The antiarrhythmic activity of bis-alkoxyphenyltriazaalkanes 1 and bis-alkoxyphenyldiazaalkanes 2 was analyzed in a model of reperfusion arrhythmia in rats. It was found that the key requirements for the compounds activity in this model are the use of 2,3,4 trimethoxyphenyl aromatic pharmacophores a...