Study on pharmacokinetics and tissue distribution of the isocorydine derivative (AICD) in rats by HPLC-DAD method

• Main Authors: Yali Chen (Author), Qian Yan (Author), Mei Zhong (Author), Quanyi Zhao (Author), Junxi Liu (Author), Duolong Di (Author), Jinxia Liu (Author)
• Format: Book
• Published: Elsevier, 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A simple and effective high-performance liquid chromatography with diode-array detection method coupled with a liquid-liquid extraction pretreatment has been developed for determining the pharmacokinetics and tissue distribution of a novel structurally modified derivative (8-acetamino-isocorydine) o...