Ethyl Pyruvate Attenuates CaCl2-Induced Tubular Epithelial Cell Injury by Inhibiting Autophagy and Inflammatory Responses

• Main Authors: Jiawen Zhao (Author), Jiwen Cheng (Author), Chengyang Li (Author), Mingbin Xu (Author), Chenjun Ma (Author), Lei Qin (Author), Kai Yi (Author), Naikai Liao (Author)
• Format: Book
• Published: Karger Publishers, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Nephrolithiasis is one of the most prevalent diseases of the urinary system. Approximately 80% of human kidney stones are composed of calcium oxalate (CaOx), and hypercalciuria is one of the most common metabolic disorders. Emerging evidence indicates that autophagy and inflammatory...