Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB

Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB

Background. LBP and fractalkine are known to be involved in the pathogenesis of ARDS. This study investigated the relationship between LBP and fractalkine in LPS-induced A549 cells and rat lung tissue in an ARDS rat model. Methods. A549 cells were transfected with LBP or LBP shRNA plasmid DNA or pre...

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Main Authors: Xia Huang (Author), Yi Zeng (Author), Yujie Jiang (Author), Yueqiu Qin (Author), Weigui Luo (Author), Shulin Xiang (Author), Suren R. Sooranna (Author), Liao Pinhu (Author)
Format: Book
Published: Hindawi Limited, 2017-01-01T00:00:00Z.
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