Analysis of docosanol using GC/MS: Method development, validation, and application to ex vivo human skin permeation studies

• Main Authors: Vijay Kumar Shankar (Author), Mei Wang (Author), Srinivas Ajjarapu (Author), Praveen Kolimi (Author), Bharathi Avula (Author), Reena Murthy (Author), Ikhlas Khan (Author), Sathyanarayana Narasimha Murthy (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Docosanol is the only US Food and Drug Administration (FDA) approved over-the-counter topical product for treating recurrent oral-facial herpes simplex labialis. Validated analytical methods for docosanol are required to demonstrate the bioequivalence of docosanol topical products. A gas chromatogra...