Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations

• Main Authors: Aroon T. Chande (Author), Lavanya Rishishwar (Author), Andrew B. Conley (Author), Augusto Valderrama-Aguirre (Author), Miguel A. Medina-Rivas (Author), I. King Jordan (Author)
• Format: Book
• Published: BMC, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hispanic/Latino (HL) populations bear a disproportionately high burden of type 2 diabetes (T2D). The ability to predict T2D genetic risk using polygenic risk scores (PRS) offers great promise for improved screening and prevention. However, there are a number of complications rela...