Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management

• Asıl Yazarlar: Laura M. S. Seeber (Yazar), Ronald P. Zweemer (Yazar), René H. M. Verheijen (Yazar), Paul J. van Diest (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2010-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

In the Western world, endometrial cancer (EC) is the most common malignant tumor of the female genital tract. Solid tumors like EC outgrow their vasculature resulting in hypoxia. Tumor hypoxia is important because it renders an aggressive phenotype and leads to radio- and chemo-therapy resistance. H...