Therapeutic Targeting of AXL Receptor Tyrosine Kinase Inhibits Tumor Growth and Intraperitoneal Metastasis in Ovarian Cancer Models

• Главные авторы: Pinar Kanlikilicer (Автор), Bulent Ozpolat (Автор), Burcu Aslan (Автор), Recep Bayraktar (Автор), Nilgun Gurbuz (Автор), Cristian Rodriguez-Aguayo (Автор), Emine Bayraktar (Автор), Merve Denizli (Автор), Vianey Gonzalez-Villasana (Автор), Cristina Ivan (Автор), Ganesh L.R. Lokesh (Автор), Paola Amero (Автор), Silvia Catuogno (Автор), Monika Haemmerle (Автор), Sherry Yen-Yao Wu (Автор), Rahul Mitra (Автор), David G. Gorenstein (Автор), David E. Volk (Автор), Vittorio de Franciscis (Автор), Anil K. Sood (Автор), Gabriel Lopez-Berestein (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2017-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Despite substantial improvements in the treatment strategies, ovarian cancer is still the most lethal gynecological malignancy. Identification of drug treatable therapeutic targets and their safe and effective targeting is critical to improve patient survival in ovarian cancer. AXL receptor tyrosine...