Repurposing Disulfiram as an Antimicrobial Agent in Topical Infections

• Main Authors: Maria Lajarin-Reinares (Author), Eloy Pena-Rodríguez (Author), Mariona Cañellas-Santos (Author), Elisabet Rosell-Vives (Author), Pilar Cortés (Author), Montserrat Llagostera Casas (Author), Maria Àngels Calvo (Author), Francisco Fernandez-Campos (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antimicrobial drugs applied topically offer several advantages. However, the widespread use of antibiotics has led to increasing antimicrobial resistance. One interesting approach in the drug discovery process is drug repurposing. Disulfiram, which was originally approved as an anti-alcoholism drug,...