Huntington's Disease and Striatal Signaling

• Main Authors: Emmanuel eRoze (Author), Emma eCahill (Author), Elodie eMartin (Author), Cecilia eBonnet (Author), Peter eVanhoutte (Author), Sandrine eBetuing (Author), Jocelyne eCaboche (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Huntington's Disease (HD) is the most frequent neurodegenerative disease caused by an expansion of polyglutamines (CAG). The main clinical manifestations of HD are chorea, cognitive impairment and psychiatric disorders. The transmission of HD is autosomal dominant with a complete penetrance. HD...