Apigenin, a Single Active Component of Herbal Extract, Alleviates Xerostomia via ERα-Mediated Upregulation of AQP5 Activation

• Main Authors: Wei Wei (Author), Tingting Cao (Author), Janak L. Pathak (Author), Xintong Liu (Author), Tianjiao Mao (Author), Nobumoto Watanabe (Author), Xiaomeng Li (Author), Manli Zhang (Author), Jiang Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Xerostomia is a common symptom in menopausal women, suggesting the role of sex steroids in disease development. Shreds of literature had reported the potential use of herbal extracts to relieve xerostomia. However, a cocktail of multiple components in herbal extract makes it difficult to understand...