Glucagon-Like Peptide-1 Analog Exendin-4 Ameliorates Cocaine-Mediated Behavior by Inhibiting Toll-Like Receptor 4 Signaling in Mice

• Main Authors: Changliang Zhu (Author), Hong Tao (Author), Shikuo Rong (Author), Lifei Xiao (Author), Xinxiao Li (Author), Shucai Jiang (Author), Baorui Guo (Author), Lei Wang (Author), Jiangwei Ding (Author), Caibing Gao (Author), Haigang Chang (Author), Tao Sun (Author), Feng Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exendin-4 (Ex4), a long-lasting glucagon-like peptide-1 analog, was reported to exert favourable actions on inhibiting cocaine-associated rewarding and reinforcing effects of drug in animal models of addiction. However, the therapeutic potential of different dose of GLP-1 receptor agonist Ex4 in dif...