Structural Analysis of The OXA-48 Carbapenemase Bound to A "Poor" Carbapenem Substrate, Doripenem

Carbapenem-resistant Enterobacteriaceae are a significant threat to public health, and a major resistance determinant that promotes this phenotype is the production of the OXA-48 carbapenemase. The activity of OXA-48 towards carbapenems is a puzzling phenotype as its hydrolytic activity against dori...

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Main Authors: Krisztina M. Papp-Wallace (Author), Vijay Kumar (Author), Elise T. Zeiser (Author), Scott A. Becka (Author), Focco van den Akker (Author)
Format: Book
Published: MDPI AG, 2019-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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