Genetic polymorphisms of CYP2B6*6, CYP2C8*3 and CYP2D6*4 in vivax malaria patients from Brazilian Amazon

• Glavni autori: José Pereira de Moura Neto (Autor), Jaquelane Silva de Jesus (Autor), Marcus Vinícius Guimarães de Lacerda (Autor), Thiago de Jesus Bacha (Autor), Igor Rafael dos Santos Magalhães (Autor)
• Format: Knjiga
• Izdano: Universidade de São Paulo, 2023-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Genetic variability in the host metabolism of antimalarial drugs influenced by the polymorphisms of cytochrome P450 (CYP) could lead to significant changes in antimalarial treatment response. However, little is known about the frequency of alleles CYP2B6, CYP2C8, and CYP2D6 in an Amazonian...