Lomerizine attenuates LPS-induced acute lung injury by inhibiting the macrophage activation through reducing Ca2+ influx

• Hauptverfasser: Yunduan Song (Verfasst von), Yusen Gou (Verfasst von), Jiameng Gao (Verfasst von), Dongxin Chen (Verfasst von), Haibo Zhang (Verfasst von), Wenjuan Zhao (Verfasst von), Feng Qian (Verfasst von), Ajing Xu (Verfasst von), Yao Shen (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening lung diseases with high mortality rates, predominantly attributable to acute and severe pulmonary inflammation. Lomerizine (LMZ) is a calcium channel blocker previously used in preventing and treating migrain...