Lomerizine attenuates LPS-induced acute lung injury by inhibiting the macrophage activation through reducing Ca2+ influx

• Main Authors: Yunduan Song (Author), Yusen Gou (Author), Jiameng Gao (Author), Dongxin Chen (Author), Haibo Zhang (Author), Wenjuan Zhao (Author), Feng Qian (Author), Ajing Xu (Author), Yao Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening lung diseases with high mortality rates, predominantly attributable to acute and severe pulmonary inflammation. Lomerizine (LMZ) is a calcium channel blocker previously used in preventing and treating migrain...