Design, Synthesis, and Biological Evaluation of Novel Tomentosin Derivatives in NMDA-Induced Excitotoxicity

• Main Authors: Mohamed Zaki (Author), Mohammed Loubidi (Author), Tuğçe Bilgiç (Author), Derviş Birim (Author), Mohamed Akssira (Author), Taner Dagcı (Author), Sabine Berteina-Raboin (Author), Luciano Saso (Author), Mostafa Khouili (Author), Güliz Armagan (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

N-methyl-D-aspartate (NMDA) receptor stimulation may lead to excitotoxicity, which triggers neuronal death in brain disorders. In addition to current clinical therapeutic approaches, treatment strategies by phytochemicals or their derivatives are under investigation for neurodegenerative diseases. I...