Assessment of the physical dependence potential of difelikefalin: Randomized placebo‐controlled study in patients receiving hemodialysis

• Hauptverfasser: Robert H. Spencer (Verfasst von), Catherine Munera (Verfasst von), Megan J. Shram (Verfasst von), Frédérique Menzaghi (Verfasst von)
• Format: Buch
• Veröffentlicht: Wiley, 2023-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Difelikefalin is a selective kappa opioid receptor agonist approved for treating moderate‐to‐severe pruritus in adults undergoing hemodialysis (HD). Difelikefalin is not a controlled substance under the Controlled Substances Act. This study assessed the potential for developing physical dep...