A Randomized Controlled Intervention Trial with Danazol to Improve Telomeric and Fertility Parameters in Women with Diminished Ovarian Reserve: A Pilot Study

• Main Authors: Isabel C?rdova-Oriz (Author), Graciela Kohls (Author), Carlos Iglesias (Author), Alba M. Polonio (Author), Luc?a Chico-Sordo (Author), M?nica Toribio (Author), Marcos Meseguer (Author), Elisa Varela (Author), Antonio Pellicer (Author), Juan A. Garc?a-Velasco (Author)
• Format: Book
• Published: Mary Ann Liebert, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Most women who are treated at in vitro fertilization (IVF) clinics have trouble conceiving due to ovarian failure (OF), which seems to be associated to short telomeres and reduced or absent telomerase activity in their granulosa cells. Indeed, telomere pathways are involved in organ dysf...