Using partition analysis as a facile method to derive net clearances

Abstract Partition analysis has been described previously by W.W. Cleland to derive net rate constants and simplify the derivation of enzyme kinetic equations. Here, we show that partition analysis can be used to derive elimination and transfer (distribution) net clearances for use in pharmacokineti...

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Bibliographic Details
Main Authors: Ken Korzekwa (Author), Jaydeep Yadav (Author), Swati Nagar (Author)
Format: Book
Published: Wiley, 2022-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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