The effect of 'cytochrome P-450 2C9' and 'vitamin K epoxide reductase complex 1' genetic polymorphism upon oral anticoagulation requirements
Background Polymorphisms in the gene encoding the cytochrome P-450 2C9 enzyme (CYP2C9) are known to contribute to variability in sensitivity to Marevan. CYP2C9 is the enzyme primarily responsible for the metabolic clearance of s-enantiomer of Marevan. The vitamin K epoxide reductase complex 1 (VKORC...
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Wolters Kluwer Medknow Publications,
2018-01-01T00:00:00Z.
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A1234.567 |
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