Enhancing oocyte in vitro maturation and quality by melatonin/bilirubin cationic nanoparticles: A promising strategy for assisted reproduction techniques

• Main Authors: Haitao Xi (Author), Lihui Huang (Author), Lin Qiu (Author), Shize Li (Author), Yuqi Yan (Author), Yang Ding (Author), Yuhao Zhu (Author), Fugen Wu (Author), Xianbao Shi (Author), Junzhao Zhao (Author), Ruijie Chen (Author), Qing Yao (Author), Longfa Kou (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In assisted reproduction techniques, oocytes encounter elevated levels of reactive oxygen species (ROS) during in vitro maturation (IVM). Oxidative stress adversely affects oocyte quality, hampering their maturation, growth, and subsequent development. Thus, mitigating excessive ROS to safeguard les...