Screening for Genetic Mutations for the Early Diagnosis of Common Variable Immunodeficiency in Children With Refractory Immune Thrombocytopenia: A Retrospective Data Analysis From a Tertiary Children's Center

• Main Authors: Jingyao Ma (Author), Lingling Fu (Author), Hao Gu (Author), Zhenping Chen (Author), Jialu Zhang (Author), Shasha Zhao (Author), Xiaojing Zhu (Author), Huiqing Liu (Author), Runhui Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: This study aimed to identify common variable immunodeficiency (CVID) by high-throughput next-generation sequencing (NGS) in children with refractory immune thrombocytopenia (RITP) to facilitate early diagnosis.Methods: CVID-related genetic mutations were explored in patients with RITP during 20...