Screening for Genetic Mutations for the Early Diagnosis of Common Variable Immunodeficiency in Children With Refractory Immune Thrombocytopenia: A Retrospective Data Analysis From a Tertiary Children's Center

• Auteurs principaux: Jingyao Ma (Auteur), Lingling Fu (Auteur), Hao Gu (Auteur), Zhenping Chen (Auteur), Jialu Zhang (Auteur), Shasha Zhao (Auteur), Xiaojing Zhu (Auteur), Huiqing Liu (Auteur), Runhui Wu (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Aim: This study aimed to identify common variable immunodeficiency (CVID) by high-throughput next-generation sequencing (NGS) in children with refractory immune thrombocytopenia (RITP) to facilitate early diagnosis.Methods: CVID-related genetic mutations were explored in patients with RITP during 20...