Associations of CXCL1 gene 5'UTR variations with ovarian cancer

• Main Authors: Man Guo (Author), Chao Xu (Author), Yan-Zhe Chen (Author), Qi-Wen Sun (Author), Xin-Ying Zhao (Author), Xin Liu (Author), Yi Yang (Author), Yi-Yan Hu (Author), Fei-Feng Li (Author), Shu-Lin Liu (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background There are about 2.4 hundred thousand new cases and 1.5 hundred thousand deaths of ovarian cancer (OC) annually in the world. Chronic inflammation is a risk factor for OC. C-X-C motif chemokine ligand 1 (CXCL1) defects may facilitate inflammation and transactivate EGFR in ovarian...