Predicting Preference of Transcription Factors for Methylated DNA Using Sequence Information

• 主要な著者: Meng-Lu Liu (著者), Wei Su (著者), Jia-Shu Wang (著者), Yu-He Yang (著者), Hui Yang (著者), Hao Lin (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2020-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Transcription factors play key roles in cell-fate decisions by regulating 3D genome conformation and gene expression. The traditional view is that methylation of DNA hinders transcription factors binding to them, but recent research has shown that many transcription factors prefer to bind to methyla...