DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage

• मुख्य लेखकों: DeGeest Koen (लेखक), Holtan Nicholas (लेखक), Futscher Bernard W (लेखक), Watts George S (लेखक), Domann Frederick E (लेखक), Rose Stephen L (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2008-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hypermethylation of promoter CpG islands with associated loss of gene expression, and hypomethylation of CpG-rich repetitive elements that may destabilize the genome are common events in most, if not all, epithelial cancers.</p>...