DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage

• Main Authors: DeGeest Koen (Author), Holtan Nicholas (Author), Futscher Bernard W (Author), Watts George S (Author), Domann Frederick E (Author), Rose Stephen L (Author)
• Format: Book
• Published: BMC, 2008-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hypermethylation of promoter CpG islands with associated loss of gene expression, and hypomethylation of CpG-rich repetitive elements that may destabilize the genome are common events in most, if not all, epithelial cancers.</p>...