Dipeptide cholecystokinin-4 analog attenuates anxiety in "high-emotional" mice BALB/c and in ethanol-withdrawn rats: comparison with phenazepam

• Main Authors: L. G. Kolik (Author), A. V. Nadorova (Author), T. A. Gudasheva (Author), V. A. Martyanov (Author), S. B. Seredenin (Author)
• Formato: Livro
• Publicado em: LLC "Publisher OKI", 2017-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Anxiolytic effects of dipeptide endogenous cholecystokinin tetrapeptide analogue GB-115 at the dose range 0,25-2,0 mg/ kg after oral administration were studied in rodents with high emotionality. In "elevated plus-maze" test GB-115 anxiolytic activity comparable with phenazepam was shown i...