Development and effects of tacrolimus-loaded nanoparticles on the inhibition of corneal allograft rejection

• Main Authors: Qianni Wu (Author), Dong Liu (Author), Xulin Zhang (Author), Dongni Wang (Author), Meimei DongYe (Author), Wan Chen (Author), Duoru Lin (Author), Fangming Zhu (Author), Weirong Chen (Author), Haotian Lin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tacrolimus has been widely applied to prevent organ rejection after transplantation. However, the conventional pharmaceutical formulation of tacrolimus limits its applications in ocular therapy due to its hydrophobicity and low corneal penetrability. We optimized tacrolimus-loaded methoxy poly (ethy...