Chronic Lymphocytic Leukemia (CLL): evaluation of AKT protein kinase and microRNA gene expression related to disease pathogenesis

• Główni autorzy: Lorena Caixeta Gomes (Autor), Rodrigo Ribeiro Resende (Autor), Ricardo Cambraia Parreira (Autor), Cláudia Natália Ferreira (Autor), Edna Afonso Reis (Autor), Rita Carolina Figueiredo Duarte (Autor), Luan Carlos Vieira Alves (Autor), Sergio Schusterschitz da Silva Araújo (Autor), Maria das Graças Carvalho (Autor), Adriano de Paula Sabino (Autor)
• Format: Książka
• Wydane: Universidade de São Paulo, 2022-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract The present study evaluated 56 patients diagnosed with Chronic Lymphocytic Leukemia (CLL) and a control group of 44 clinically healthy subjects with no previous history of leukemia. Genetic expressions of AKT and microRNAs were evaluated by quantitative PCR (qPCR). A significant increase in...