Lysophosphatidic acid induces proliferation and osteogenic differentiation of human dental pulp stem cell through lysophosphatidic acid receptor 3/extracellular signal-regulated kinase signaling axis

• Main Authors: Soon Chul Heo (Author), Bo Ram Keum (Author), Eun Jin Seo (Author), Jinhwan Yoon (Author), Sanghwa Jeong (Author), Gabor J. Tigyi (Author), Derek Norman (Author), Il Ho Jang (Author), Hyung Joon Kim (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Human dental pulp stem cells (hDPSCs) possess excellent proliferative and osteogenic differentiation potentials. This study aimed to elucidate the role of lysophosphatidic acid (LPA) signaling in the proliferation and osteogenic differentiation of hDPSCs. Materials and methods: h...