Biocompatible, Multi-Mode, Fluorescent, <em>T</em>₂ MRI Contrast Magnetoelectric-Silica Nanoparticles (MagSiNs), for On-Demand Doxorubicin Delivery to Metastatic Cancer Cells

• Main Authors: Margo Waters (Author), Juliane Hopf (Author), Emma Tam (Author), Stephanie Wallace (Author), Jordan Chang (Author), Zach Bennett (Author), Hadrian Aquino (Author), Ryan K. Roeder (Author), Paul Helquist (Author), M. Sharon Stack (Author), Prakash D. Nallathamby (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is a need to improve current cancer treatment regimens to reduce systemic toxicity, to positively impact the quality-of-life post-treatment. We hypothesized the negation of off-target toxicity of anthracyclines (e.g., Doxorubicin) by delivering Doxorubicin on magneto-electric silica nanopartic...