Lido-OH, a Hydroxyl Derivative of Lidocaine, Produced a Similar Local Anesthesia Profile as Lidocaine With Reduced Systemic Toxicities

Background: lidocaine is one of the most commonly used local anesthetics for the treatment of pain and arrhythmia. However, it could cause systemic toxicities when plasma concentration is raised. To reduce lidocaine's toxicity, we designed a hydroxyl derivative of lidocaine (lido-OH), and its l...

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Main Authors: Qinqin Yin (Author), Weiyi Zhang (Author), Bowen Ke (Author), Jin Liu (Author), Wensheng Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
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