Implementation strategies for hospital-based probiotic administration in a stepped-wedge cluster randomized trial design for preventing hospital-acquired Clostridioides difficile infection

• Main Authors: Lauren C. Bresee (Author), Nicole Lamont (Author), Wrechelle Ocampo (Author), Jayna Holroyd-Leduc (Author), Deana Sabuda (Author), Jenine Leal (Author), Bruce Dalton (Author), Jaime Kaufman (Author), Bayan Missaghi (Author), Joseph Kim (Author), Oscar E. Larios (Author), Elizabeth Henderson (Author), Maitreyi Raman (Author), Jared R. Fletcher (Author), Peter Faris (Author), Scott Kraft (Author), Ye Shen (Author), Thomas Louie (Author), John M. Conly (Author)
• Format: Book
• Published: BMC, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Clostridioides difficile infection (CDI) is associated with considerable morbidity and mortality in hospitalized patients, especially among older adults. Probiotics have been evaluated to prevent hospital-acquired (HA) CDI in patients who are receiving systemic antibiotics, but t...