The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?

Abstract Cellular senescence is a state of irreversible cell cycle arrest that can be induced by a variety of potentially oncogenic stimuli, including DNA damage. Hence, senescence has long been considered to suppress tumorigenesis, acting as a guardian of homeostasis. However, recent studies have r...

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3rd Floor Main Library

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