Essential role of germ cell glycerol-3-phosphate phosphatase for sperm health, oxidative stress control and male fertility in mice

• Main Authors: Abel Oppong (Author), Yat Hei Leung (Author), Anindya Ghosh (Author), Marie-Line Peyot (Author), Marilène Paquet (Author), Carlos Morales (Author), Hugh J. Clarke (Author), Fahd Al-Mulla (Author), Alexandre Boyer (Author), S. R. Murthy Madiraju (Author), Derek Boerboom (Author), Cristian O'Flaherty (Author), Marc Prentki (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Obesity, diabetes and high-calorie diets are associated with defective sperm function and lowered male fertility. Mature spermatozoa primarily use fructose and glucose, and glucose and glycerol metabolism are important for sperm function. We recently discovered a novel mammalian enzyme,...