Novel Fas-TNFR chimeras that prevent Fas ligand-mediated kill and signal synergistically to enhance CAR T cell efficacy
The hostile tumor microenvironment limits the efficacy of adoptive cell therapies. Activation of the Fas death receptor initiates apoptosis and disrupting these receptors could be key to increasing CAR T cell efficacy. We screened a library of Fas-TNFR proteins identifying several novel chimeras tha...
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Asıl Yazarlar: | , , , , , , , , , |
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Materyal Türü: | Kitap |
Baskı/Yayın Bilgisi: |
Elsevier,
2023-06-01T00:00:00Z.
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Internet
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Yer Numarası: |
A1234.567 |
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Kopya Bilgisi 1 | Kütüphanede |