Effect of first-line biologic initiation on glucocorticoid exposure in children hospitalized with new-onset systemic juvenile idiopathic arthritis: emulation of a pragmatic trial using observational data

• 主要な著者: Rosemary G. Peterson (著者), Rui Xiao (著者), Hannah Katcoff (著者), Brian T. Fisher (著者), Pamela F. Weiss (著者)
• フォーマット: 図書
• 出版事項: BMC, 2021-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Glucocorticoid exposure is a significant driver of morbidity in children with systemic juvenile idiopathic arthritis (sJIA). We determined the effect of early initiation of biologic therapy (IL-1 or IL-6 inhibition) on glucocorticoid exposure in hospitalized patients with new-ons...