Analgesic Effects of Duloxetine on Formalin-Induced Hyperalgesia and Its Underlying Mechanisms in the CeA

• Main Authors: Lie Zhang (Author), Jun-Bin Yin (Author), Wei Hu (Author), Wen-Jun Zhao (Author), Qing-Rong Fan (Author), Zhi-Chun Qiu (Author), Ming-Jie He (Author), Tan Ding (Author), Yan Sun (Author), Alan D. Kaye (Author), En-Ren Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In rodents, the amygdala has been proposed to serve as a key center for the nociceptive perception. Previous studies have shown that extracellular signal-regulated kinase (ERK) signaling cascade in the central nucleus of amygdala (CeA) played a functional role in inflammation-induced peripheral hype...