LPS Primes Brain Responsiveness to High Mobility Group Box-1 Protein

• Main Authors: Verena Peek (Author), Lois M. Harden (Author), Jelena Damm (Author), Ferial Aslani (Author), Stephan Leisengang (Author), Joachim Roth (Author), Rüdiger Gerstberger (Author), Marita Meurer (Author), Maren von Köckritz-Blickwede (Author), Sabine Schulz (Author), Bernhard Spengler (Author), Christoph Rummel (Author)
• 格式: 圖書
• 出版: MDPI AG, 2021-06-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

High mobility group box (HMGB)1 action contributes to late phases of sepsis, but the effects of increased endogenous plasma HMGB1 levels on brain cells during inflammation are unclear. Here, we aimed to further investigate the role of HMGB1 in the brain during septic-like lipopolysaccharide-induced...