Pharmacokinetics of Phenprocoumon in Emergency Situations-Results of the Prospective Observational RADOA-Registry (Reversal Agent Use in Patients Treated with Direct Oral Anticoagulants or Vitamin K Antagonists Registry)

• Main Authors: Edelgard Lindhoff-Last (Author), Ingvild Birschmann (Author), Antonia J. Bidenharn (Author), Joachim Kuhn (Author), Simone Lindau (Author), Stavros Konstantinides (Author), Oliver Grottke (Author), Ulrike Nowak-Göttl (Author), Jessica Lucks (Author), Barbara Zydek (Author), Christian von Heymann (Author), Ariane Sümnig (Author), Jan Beyer-Westendorf (Author), Sebastian Schellong (Author), Patrick Meybohm (Author), Andreas Greinacher (Author), Eva Herrmann (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Phenprocoumon has been used as an oral anticoagulant in patients with thromboembolic disease for more than 40 years. So far its pharmacokinetics have not been analyzed in emergency situations. Methods: Phenprocoumon-treated patients with major bleeding or urgent surgery were included in...