Nitric oxide modulates interleukin-2-induced proliferation in CTLL-2 cells

• Main Authors: J. Padrón (Author), L. Glaría (Author), O. Martinez (Author), M. Torres (Author), E. Lopez (Author), R. Delgado (Author), L. Caveda (Author), A. Rojas (Author)
• Format: Book
• Published: Hindawi Limited, 1996-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The role of the L-arginine-nitric oxide metabolic pathway was explored for interleukin-2-induced proliferation in the cytotoxic T lymphocyte clone CTLL-2. Specific inhibition of nitric oxide synthase significantly diminished, in a concentration-dependent manner, 3H-thymidine uptake of CTLL-2 cells i...