Biological evaluation, docking and molecular dynamic simulation of some novel diaryl urea derivatives bearing quinoxalindione moiety

• Main Authors: Sedighe Sadeghian-Rizi (Author), Ghadamali Ali Khodarahmi (Author), Amirhossein Sakhteman (Author), Ali Jahanian-Najafabadi (Author), Mahboubeh Rostami (Author), Mahmoud Mirzaei (Author), Farshid Hassanzadeh (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study a series of diarylurea derivatives containing quinoxalindione group were biologically evaluated for their cytotoxic activities using MTT assay against MCF-7 and HepG2 cell lines. Antibacterial activities of these compounds were also evaluated by Microplate Alamar Blue Assay (MABA) agai...